TimeXNet Web - Identify active gene networks and pathways using time-course biological data

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KEGG Pathway Enrichment

Job Name:

LPS Response in Mouse TRIF KO BMDCs

Current Gene List:

Input Gene List

Background List:

Whole Genome

137 chart records

Note: Only the top 1000 records are shown here

Category	Term	Count	%	P-value	Benjamini
KEGG_PATHWAY	mmu04668:TNF signaling pathway	56	6.1	3.1e-31	8.0e-29
KEGG_PATHWAY	mmu05142:Chagas disease (American trypanosomiasis)	53	5.8	1.4e-29	1.8e-27
KEGG_PATHWAY	mmu05200:Pathways in cancer	107	11.6	1.5e-29	1.3e-27
KEGG_PATHWAY	mmu05161:Hepatitis B	62	6.7	9.2e-29	5.9e-27
KEGG_PATHWAY	mmu04722:Neurotrophin signaling pathway	56	6.1	4.8e-28	2.4e-26
KEGG_PATHWAY	mmu04620:Toll-like receptor signaling pathway	51	5.5	5.8e-28	2.5e-26
KEGG_PATHWAY	mmu04010:MAPK signaling pathway	80	8.7	6.6e-27	2.4e-25
KEGG_PATHWAY	mmu05205:Proteoglycans in cancer	70	7.6	5.1e-26	1.6e-24
KEGG_PATHWAY	mmu05133:Pertussis	42	4.6	1.3e-25	3.6e-24
KEGG_PATHWAY	mmu05169:Epstein-Barr virus infection	71	7.7	4.1e-25	1.1e-23
KEGG_PATHWAY	mmu05145:Toxoplasmosis	49	5.3	3.3e-23	7.7e-22
KEGG_PATHWAY	mmu04064:NF-kappa B signaling pathway	45	4.9	9.0e-23	1.9e-21
KEGG_PATHWAY	mmu05152:Tuberculosis	59	6.4	3.1e-21	6.0e-20
KEGG_PATHWAY	mmu05164:Influenza A	58	6.3	3.7e-21	6.7e-20
KEGG_PATHWAY	mmu04621:NOD-like receptor signaling pathway	33	3.6	8.3e-21	1.4e-19
KEGG_PATHWAY	mmu04068:FoxO signaling pathway	49	5.3	1.8e-19	2.9e-18
KEGG_PATHWAY	mmu04660:T cell receptor signaling pathway	43	4.7	1.9e-19	2.9e-18
KEGG_PATHWAY	mmu04380:Osteoclast differentiation	47	5.1	4.4e-19	6.2e-18
KEGG_PATHWAY	mmu04662:B cell receptor signaling pathway	35	3.8	4.9e-19	6.6e-18
KEGG_PATHWAY	mmu04915:Estrogen signaling pathway	41	4.5	9.0e-19	1.1e-17
KEGG_PATHWAY	mmu04062:Chemokine signaling pathway	59	6.4	1.1e-18	1.3e-17
KEGG_PATHWAY	mmu05215:Prostate cancer	38	4.1	5.7e-18	6.6e-17
KEGG_PATHWAY	mmu05160:Hepatitis C	47	5.1	1.4e-17	1.6e-16
KEGG_PATHWAY	mmu05220:Chronic myeloid leukemia	34	3.7	1.5e-17	1.6e-16
KEGG_PATHWAY	mmu05140:Leishmaniasis	32	3.5	2.0e-17	2.1e-16
KEGG_PATHWAY	mmu05212:Pancreatic cancer	32	3.5	3.5e-17	3.5e-16
KEGG_PATHWAY	mmu05166:HTLV-I infection	69	7.5	6.6e-17	1.0e-15
KEGG_PATHWAY	mmu05162:Measles	46	5.0	8.4e-17	1.0e-15
KEGG_PATHWAY	mmu05210:Colorectal cancer	31	3.4	2.1e-16	2.0e-15
KEGG_PATHWAY	mmu04917:Prolactin signaling pathway	33	3.6	2.4e-16	1.9e-15
KEGG_PATHWAY	mmu04012:ErbB signaling pathway	36	3.9	2.4e-16	1.8e-15
KEGG_PATHWAY	mmu04910:Insulin signaling pathway	45	4.9	1.9e-15	1.5e-14
KEGG_PATHWAY	mmu04210:Apoptosis	29	3.1	2.7e-15	2.1e-14
KEGG_PATHWAY	mmu05132:Salmonella infection	33	3.6	2.7e-15	2.1e-14
KEGG_PATHWAY	mmu05203:Viral carcinogenesis	59	6.4	5.4e-15	4.0e-14
KEGG_PATHWAY	mmu04664:Fc epsilon RI signaling pathway	30	3.3	1.7e-14	1.2e-13
KEGG_PATHWAY	mmu04912:GnRH signaling pathway	34	3.7	2.3e-14	1.6e-13
KEGG_PATHWAY	mmu05168:Herpes simplex infection	53	5.8	1.8e-13	1.2e-12
KEGG_PATHWAY	mmu05134:Legionellosis	26	2.8	5.1e-13	3.3e-12
KEGG_PATHWAY	mmu04071:Sphingolipid signaling pathway	38	4.1	2.1e-12	1.4e-11
KEGG_PATHWAY	mmu04510:Focal adhesion	51	5.5	2.2e-12	1.4e-11
KEGG_PATHWAY	mmu04015:Rap1 signaling pathway	52	5.6	2.3e-12	1.4e-11
KEGG_PATHWAY	mmu05221:Acute myeloid leukemia	25	2.7	2.8e-12	1.6e-11
KEGG_PATHWAY	mmu04630:Jak-STAT signaling pathway	41	4.5	4.4e-12	2.5e-11
KEGG_PATHWAY	mmu04151:PI3K-Akt signaling pathway	70	7.6	5.4e-12	3.1e-11
KEGG_PATHWAY	mmu04622:RIG-I-like receptor signaling pathway	27	2.9	8.1e-12	4.5e-11
KEGG_PATHWAY	mmu04370:VEGF signaling pathway	25	2.7	1.7e-11	9.0e-11
KEGG_PATHWAY	mmu05223:Non-small cell lung cancer	24	2.6	2.3e-11	1.2e-10
KEGG_PATHWAY	mmu04650:Natural killer cell mediated cytotoxicity	33	3.6	3.7e-11	1.9e-10
KEGG_PATHWAY	mmu04060:Cytokine-cytokine receptor interaction	54	5.9	4.6e-11	2.3e-10
KEGG_PATHWAY	mmu05222:Small cell lung cancer	29	3.1	5.9e-11	2.9e-10
KEGG_PATHWAY	mmu04611:Platelet activation	37	4.0	6.0e-11	2.9e-10
KEGG_PATHWAY	mmu04141:Protein processing in endoplasmic reticulum	42	4.6	1.6e-10	7.8e-10
KEGG_PATHWAY	mmu04920:Adipocytokine signaling pathway	26	2.8	2.3e-10	1.1e-9
KEGG_PATHWAY	mmu05213:Endometrial cancer	22	2.4	2.5e-10	1.2e-9
KEGG_PATHWAY	mmu04914:Progesterone-mediated oocyte maturation	28	3.0	8.1e-10	3.7e-9
KEGG_PATHWAY	mmu04932:Non-alcoholic fatty liver disease (NAFLD)	39	4.2	1.0e-9	4.5e-9
KEGG_PATHWAY	mmu04550:Signaling pathways regulating pluripotency of stem cells	36	3.9	1.2e-9	5.4e-9
KEGG_PATHWAY	mmu05211:Renal cell carcinoma	24	2.6	1.6e-9	6.9e-9
KEGG_PATHWAY	mmu04024:cAMP signaling pathway	44	4.8	2.5e-9	1.1e-8
KEGG_PATHWAY	mmu04931:Insulin resistance	31	3.4	3.0e-9	1.2e-8
KEGG_PATHWAY	mmu04066:HIF-1 signaling pathway	30	3.3	3.1e-9	1.3e-8
KEGG_PATHWAY	mmu04014:Ras signaling pathway	48	5.2	3.7e-9	1.5e-8
KEGG_PATHWAY	mmu05219:Bladder cancer	18	2.0	8.2e-9	3.3e-8
KEGG_PATHWAY	mmu04022:cGMP-PKG signaling pathway	39	4.2	1.3e-8	5.1e-8
KEGG_PATHWAY	mmu04921:Oxytocin signaling pathway	37	4.0	1.6e-8	6.1e-8
KEGG_PATHWAY	mmu05202:Transcriptional misregulation in cancer	38	4.1	1.8e-8	7.0e-8
KEGG_PATHWAY	mmu05214:Glioma	22	2.4	2.8e-8	1.1e-7
KEGG_PATHWAY	mmu05146:Amoebiasis	30	3.3	5.7e-8	2.1e-7
KEGG_PATHWAY	mmu05014:Amyotrophic lateral sclerosis (ALS)	19	2.1	6.0e-8	2.2e-7
KEGG_PATHWAY	mmu04923:Regulation of lipolysis in adipocytes	20	2.2	7.4e-8	2.7e-7
KEGG_PATHWAY	mmu05020:Prion diseases	15	1.6	7.7e-8	2.7e-7
KEGG_PATHWAY	mmu05144:Malaria	18	2.0	1.3e-7	4.6e-7
KEGG_PATHWAY	mmu05321:Inflammatory bowel disease (IBD)	20	2.2	1.4e-7	4.8e-7
KEGG_PATHWAY	mmu04520:Adherens junction	22	2.4	2.1e-7	7.0e-7
KEGG_PATHWAY	mmu04110:Cell cycle	30	3.3	2.2e-7	7.4e-7
KEGG_PATHWAY	mmu04350:TGF-beta signaling pathway	24	2.6	2.5e-7	8.2e-7
KEGG_PATHWAY	mmu05231:Choline metabolism in cancer	26	2.8	4.8e-7	1.6e-6
KEGG_PATHWAY	mmu04114:Oocyte meiosis	27	2.9	7.5e-7	2.4e-6
KEGG_PATHWAY	mmu04919:Thyroid hormone signaling pathway	27	2.9	1.3e-6	4.2e-6
KEGG_PATHWAY	mmu04320:Dorso-ventral axis formation	12	1.3	1.9e-6	5.8e-6
KEGG_PATHWAY	mmu04810:Regulation of actin cytoskeleton	40	4.3	2.1e-6	6.4e-6
KEGG_PATHWAY	mmu05143:African trypanosomiasis	14	1.5	2.2e-6	6.7e-6
KEGG_PATHWAY	mmu04623:Cytosolic DNA-sensing pathway	19	2.1	2.7e-6	8.3e-6
KEGG_PATHWAY	mmu05206:MicroRNAs in cancer	47	5.1	3.4e-6	1.0e-5
KEGG_PATHWAY	mmu04720:Long-term potentiation	19	2.1	4.5e-6	1.3e-5
KEGG_PATHWAY	mmu04670:Leukocyte transendothelial migration	27	2.9	5.1e-6	1.5e-5
KEGG_PATHWAY	mmu04930:Type II diabetes mellitus	16	1.7	7.8e-6	2.3e-5
KEGG_PATHWAY	mmu04750:Inflammatory mediator regulation of TRP channels	27	2.9	1.1e-5	3.2e-5
KEGG_PATHWAY	mmu05230:Central carbon metabolism in cancer	18	2.0	1.2e-5	3.4e-5
KEGG_PATHWAY	mmu04666:Fc gamma R-mediated phagocytosis	21	2.3	1.3e-5	3.5e-5
KEGG_PATHWAY	mmu04540:Gap junction	21	2.3	1.8e-5	5.1e-5
KEGG_PATHWAY	mmu04144:Endocytosis	45	4.9	2.1e-5	5.8e-5
KEGG_PATHWAY	mmu04730:Long-term depression	17	1.8	2.6e-5	7.0e-5
KEGG_PATHWAY	mmu04270:Vascular smooth muscle contraction	26	2.8	3.8e-5	0.0001
KEGG_PATHWAY	mmu05218:Melanoma	18	2.0	5.2e-5	0.00014
KEGG_PATHWAY	mmu05100:Bacterial invasion of epithelial cells	19	2.1	5.3e-5	0.00014
KEGG_PATHWAY	mmu05216:Thyroid cancer	11	1.2	7.0e-5	0.00018
KEGG_PATHWAY	mmu04115:p53 signaling pathway	17	1.8	8.9e-5	0.00023
KEGG_PATHWAY	mmu04728:Dopaminergic synapse	26	2.8	9.5e-5	0.00024
KEGG_PATHWAY	mmu04261:Adrenergic signaling in cardiomyocytes	28	3.0	9.6e-5	0.00024
KEGG_PATHWAY	mmu04360:Axon guidance	25	2.7	0.00014	0.00034
KEGG_PATHWAY	mmu04725:Cholinergic synapse	22	2.4	0.00036	0.00089
KEGG_PATHWAY	mmu04916:Melanogenesis	20	2.2	0.00044	0.0011
KEGG_PATHWAY	mmu04640:Hematopoietic cell lineage	18	2.0	0.00046	0.0011
KEGG_PATHWAY	mmu04310:Wnt signaling pathway	25	2.7	0.00055	0.0013
KEGG_PATHWAY	mmu05323:Rheumatoid arthritis	17	1.8	0.001	0.0024
KEGG_PATHWAY	mmu05340:Primary immunodeficiency	10	1.1	0.0014	0.0034
KEGG_PATHWAY	mmu04390:Hippo signaling pathway	25	2.7	0.0015	0.0035
KEGG_PATHWAY	mmu04713:Circadian entrainment	18	2.0	0.0028	0.0064
KEGG_PATHWAY	mmu04120:Ubiquitin mediated proteolysis	23	2.5	0.0032	0.0073
KEGG_PATHWAY	mmu04152:AMPK signaling pathway	21	2.3	0.004	0.009
KEGG_PATHWAY	mmu04960:Aldosterone-regulated sodium reabsorption	10	1.1	0.0048	0.011
KEGG_PATHWAY	mmu04020:Calcium signaling pathway	26	2.8	0.0075	0.017
KEGG_PATHWAY	mmu04150:mTOR signaling pathway	12	1.3	0.0086	0.019
KEGG_PATHWAY	mmu04970:Salivary secretion	14	1.5	0.01	0.023
KEGG_PATHWAY	mmu04723:Retrograde endocannabinoid signaling	17	1.8	0.011	0.023
KEGG_PATHWAY	mmu04530:Tight junction	21	2.3	0.011	0.023
KEGG_PATHWAY	mmu04925:Aldosterone synthesis and secretion	15	1.6	0.011	0.023
KEGG_PATHWAY	mmu04918:Thyroid hormone synthesis	13	1.4	0.012	0.025
KEGG_PATHWAY	mmu04710:Circadian rhythm	8	0.9	0.012	0.025
KEGG_PATHWAY	mmu04971:Gastric acid secretion	13	1.4	0.015	0.031
KEGG_PATHWAY	mmu00220:Arginine biosynthesis	6	0.7	0.017	0.035
KEGG_PATHWAY	mmu05010:Alzheimer's disease	24	2.6	0.021	0.043
KEGG_PATHWAY	mmu05031:Amphetamine addiction	12	1.3	0.022	0.043
KEGG_PATHWAY	mmu05416:Viral myocarditis	13	1.4	0.029	0.059
KEGG_PATHWAY	mmu04924:Renin secretion	12	1.3	0.032	0.063
KEGG_PATHWAY	mmu03013:RNA transport	22	2.4	0.043	0.084
KEGG_PATHWAY	mmu05030:Cocaine addiction	9	1.0	0.048	0.092
KEGG_PATHWAY	mmu05150:Staphylococcus aureus infection	9	1.0	0.053	0.1
KEGG_PATHWAY	mmu04962:Vasopressin-regulated water reabsorption	8	0.9	0.063	0.12
KEGG_PATHWAY	mmu05412:Arrhythmogenic right ventricular cardiomyopathy (ARVC)	11	1.2	0.068	0.13
KEGG_PATHWAY	mmu04922:Glucagon signaling pathway	14	1.5	0.071	0.13
KEGG_PATHWAY	mmu05034:Alcoholism	24	2.6	0.076	0.14
KEGG_PATHWAY	mmu04612:Antigen processing and presentation	12	1.3	0.077	0.14
KEGG_PATHWAY	mmu05414:Dilated cardiomyopathy	12	1.3	0.082	0.15
KEGG_PATHWAY	mmu04724:Glutamatergic synapse	15	1.6	0.096	0.17